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本文通过火箭电泳法测定30例正常人血浆纤维连结蛋白(Fn),其含量为289.3±38.7mg/L(x±s),其中各种肝病183例,除急性肝炎含量高于正常对照组外,慢活肝、肝硬化失代偿,原发性肝癌,Fn值均明显低于正常对照组,有显著差异(P<0.05),以肝硬化失代偿为著。同时测定常规肝功、血浆蛋白,其与Fn值,肝病病程均无明显相关性,84例甘胆酸(CG)测定,其结果与Fn呈负相关,提示血浆Fn与CG同样可做为判断肝硬化代偿功能及预后的指标之一。
In this paper, 30 cases of normal human plasma fibronectin (Fn), the content of which was 289.3 ± 38.7mg / L (x ± s), of which 183 cases of various liver diseases, except acute hepatitis content higher than the normal control group , Chronic liver failure, decompensation of liver cirrhosis, primary liver cancer, Fn values were significantly lower than the normal control group, there was a significant difference (P <0.05), the loss of liver cirrhosis as a. There was no significant correlation between Fn value and liver disease course, and 84 cases of CG were measured. The results were negatively correlated with Fn, suggesting that plasma Fn and CG could be used as the same judgment One of the indicators of compensatory function and prognosis of cirrhosis.