急性白血病的化学药物治疗

• 作 者: 沈泽霜
• 机 构: 湖南医学院附属二院内科教研组
• 出 处: 湖南医学
• 发表日期: 1986年02期
• 关键词: 急性白血病 化学药物治疗 无病生存率 细胞增殖周期 联合化疗 诱导缓解 脑膜白血病 初次治疗 完全缓解率 诱导治疗

自60年代应用联合化疗以来,急性白血病(AL)的预后已大有改善。目前,一些先进国家的儿童急性淋巴细胞白血病(ALL)的初次治疗完全缓解率已达90％以上,5年无病生存率可达50％;急性粒细胞白血病(AML)的预后虽不及ALL满意,其初治缓解率也可达60～80％,5年无病生存率也可达20％。国内也有不少AL经化疗后生存3年以上病例的报道。

The prognosis for acute leukemia (AL) has improved dramatically since the introduction of combination chemotherapy in the 1960s. At present, the complete remission rate of initial treatment of childhood acute lymphoblastic leukemia (ALL) in some advanced countries has reached more than 90%, and the 5-year disease-free survival rate can reach 50%. The prognosis of acute myeloid leukemia (AML) is not as satisfactory as ALL , Its initial remission rate up to 60 ~ 80%, 5-year disease-free survival rate of up to 20%. There are many domestic AL AL ​​3 after surviving more than 3 reports of chemotherapy.