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血小板在动脉粥样硬化、血栓形成及急性冠脉综合征中起关键作用。纤维蛋白原受体的完整是血小板聚集的前提 ,此受体由二种血小板膜糖蛋白 (ＧＰ)组成 :ＧＰⅡｂ和ＧＰⅢａ。血小板膜ＧＰⅡｂ/Ⅲａ是纤维蛋白原受体 ,在血栓形成中起重要作用。随机试验表明选择性抑制此受体可有
Platelets play a key role in atherosclerosis, thrombosis and acute coronary syndrome. Integrity of fibrinogen receptors is a prerequisite for platelet aggregation, which consists of two platelet membrane glycoproteins (GPs): GPIIb and GPIIIa. Platelet membrane GP Ⅱ b / Ⅲ a is a fibrinogen receptor that plays an important role in thrombosis. Randomized trials have shown that selective inhibition of this receptor is possible