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本文报告应用酶联免疫吸附试验(ELISA)法对百色地区513例乙型肝炎病毒(HBV)感染者进行的丁型肝炎抗原(HDAg)检测,阳性率为3.90%(20/513),其中男性4.34%(15/346),女性2.99%(5/167)。表明百色地区是丁型肝炎(丁肝)流行区。HDAg 的检出率与 HBV 感染者的年龄、性别、居住环境无关(P>0.05)。在 HBV 感染的各型肝炎中,除肝硬化和重型肝炎外,原发性肝癌、慢迁肝、慢活肝和慢性乙型肝炎表面抗原(HBsAg)携带者均检出 HDAg,且原发性肝癌、慢活肝和慢迁肝的 HDAg 阳性率明显高于慢性 HBsAg 携带者(前两者 P 值分别为0.005和0.02,后者χ~2=17.00,P<0.005),说明 HDAg 对 HBV 感染的慢性肝炎和原发性肝癌起补助作用。
This article reports the hepatitis B antigen (HDAg) detection of 513 patients with hepatitis B virus infection in Baise area by ELISA (ELISA), the positive rate was 3.90% (20/513), of which male 4.34% (15/346) and females 2.99% (5/167). Show that Baise is hepatitis D (D) epidemic area. The detection rate of HDAg is not related to the age, sex and living environment of HBV infected persons (P> 0.05). Among HBV-infected hepatitis types, HDAg is detected in primary liver cancer, slow-moving liver, slow-living liver and chronic hepatitis B surface antigen (HBsAg) carriers in addition to cirrhosis and severe hepatitis, and primary The HDAg positive rates of HCC, slow-moving liver and slow-moving liver were significantly higher than those of chronic HBsAg carriers (P values were 0.005 and 0.02 for the former two, respectively, while the latter for χ ~ 2 = 17.00, P <0.005) Chronic hepatitis and primary liver cancer play a supporting role.