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该院1990年1月至1995年12月收治了120例老年深部念珠菌感染患者，应用氟康唑治疗并进行分析，探讨其特点，用3％过氧化氢溶液嗽口后咯出或经气管导管吸取痰标本，连续3次以上痰真菌培养为念珠菌，并结合临床确诊。口腔粘膜刮取物送真菌直接镜检发现菌丝和孢子，培养为念珠菌确诊。全部病例均采用氟康唑治疗。结果：22例口腔念珠菌病患者均治愈。98例肺部念珠菌病患者治愈87例，死亡11例，病死率11．2％。真菌清除率90％，治疗中14例出现轻度恶心、3例呕吐，4例食欲减退。结论：对老年人应提高真菌感染的警觉性，早期诊断，及时应用抗真菌药物。
The hospital from January 1990 to December 1995 admitted 120 cases of elderly patients with deep Candida infection, the application of fluconazole treatment and analysis to explore the characteristics of 3% hydrogen peroxide solution after mouth or cough through the trachea Catheters to absorb sputum specimens, continuous sputum fungal culture for Candida 3 times, combined with clinical diagnosis. Oral mucosal scraping fungi sent directly to mycelium and spores found microscopy, culture for the diagnosis of Candida. All cases were treated with fluconazole. Results: Twenty-two patients with oral candidiasis were cured. 98 patients with pulmonary candidiasis were cured in 87 cases, 11 died, the mortality rate of 11.2%. 90% fungal clearance, 14 cases of mild nausea, 3 cases of vomiting, 4 cases of loss of appetite. Conclusion: The elderly should be alert to enhance fungal infection, early diagnosis, timely application of antifungal drugs.