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目的 观察慢性肝炎（ＣＨ） 高压氧（ ＨＢＯ） 治疗前后患者的免疫功能、肝组织中ＨＢｓＡｇ 、ＨＢｃＡｇ 变化。方法：用纯氧单仓治疗（２－５ＭＰａ ，２ｈ／ｄ ，１０ｄ／ｃｙｃ ，６ｃｙｃ）３０ 例ＣＨ，治疗前后用美国ＢＥＣＭＡＮ 公司生产ＡｒｒａｙＴＭＰｒｏｔｅｉｎ Ｓｙｓｔｅｍ ３６０ 测全部患者静脉血白蛋白（ Ａ） 、γ球蛋白（γ） 、ｌｇＡ、ｌｇＧ、ｌｇＭ、和补体Ｃ３ 、Ｃ４ ；二次肝穿刺活检，ＡＢＣ 法检测肝组织中ＨＢｓＡｇ 、ＨＢｃＡｇ 。取算术均数行ｔ 检验。结果：ＨＢＯ 治疗后静脉血γ、ｌｇＧ、ｌｇＭ、明显降低，Ａ、Ｃ３ 明显升高，治疗前后差异显著（ Ｐ＜０－０５） ；肝组织中ＨＢｓＡｇ 、ＨＢｃＡｇ 变化不明显，治疗前后差异不显著（ Ｐ＞ ０－０５） 。结论：ＨＢＯ 治疗ＣＨ，可抑制患者的免疫功能，对ＨＢｓＡｇ 、ＨＢｃＡｇ 抑制作用不明显
Objective To observe the immune function of patients with chronic hepatitis (CH) before and after HBO treatment and the changes of HBsAg and HBcAg in liver tissue. Methods: Thirty cases of CH (2-5MPa, 2h / d, 10d / cyc, 6cyc) were treated with pure oxygen in a single warehouse. ArrayTMProtein System 360 manufactured by BECMAN Company was used to measure venous blood albumin (A) (Γ), lgA, lgG, lgM, and complement C3, C4; liver biopsy, ABC ABC method to detect HBsAg and HBcAg in liver tissue. Take arithmetic mean t test. Results: The levels of γ, lgG and lgM in the blood of HBO after treatment were significantly lower, while the levels of A and C3 were significantly increased (P <0-05). The changes of HBsAg and HBcAg in liver tissue were not obvious, and there was no significant difference between before and after treatment (P> 0-05). Conclusion: HBO treatment of CH, can inhibit the immune function in patients with HBsAg, HBcAg inhibition was not obvious