黑色棘皮病与生殖及内分泌功能紊乱的关系

• 作 者: 周喜民
• 出 处: 国外医学.妇产科学分册
• 发表日期: 1985年02期
• 关键词: 黑色棘皮病 内分泌功能紊乱 多囊性卵巢 胰岛素抵抗 碳水化合物代谢 乳头状瘤 雄激素过多 不孕妇女 生殖内分泌 月经规则

黑色棘皮病(ACN)是一种特殊的皮肤损害,表现为色素过度沉着,皮肤增厚并伴有皮肤乳头状瘤和绒样结构。已知多囊性卵巢病(PCOD)和对胰岛素抵抗症(IR)与本病有关,但终属罕见。作者发现轻至中度的 ACN 与异常的碳水化合物代谢常见于患有 PCOD 和肥胖的妇女。作者还报道了1例16岁男性患有 ACN 和 IR(胰岛素峰值为700mIU/ml,正

Acanthosis nigricans (ACN) is a special form of skin damage characterized by hyperpigmentation, thickening of the skin and associated with papilloma and vellus-like structures. Polycystic ovary disease (PCOD) is known to be associated with insulin resistance (IR) and this disease is rarely seen. The authors found that mild to moderate ACN and abnormal carbohydrate metabolism are common in women with PCOD and obesity. The authors also reported that a 16-year-old male had ACN and IR (peak insulin 700 mIU / ml, positive