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目的:分析观察黄芪穴位注射联合疏血通注射液治疗早期糖尿病肾病的临床疗效与护理措施。方法:本研究中纳入我院住院部2014年12月—2015年12月收治早期糖尿病肾病患者共80例作为观察对象,按照入院编号奇偶性方法进行分组,分别将40例患者纳入对照组、观察组中。对照组患者用药方案为常规西药治疗,观察组患者在对照组基础上加用黄芪穴位注射联合疏血通注射液治疗。对比两组患者治疗前、治疗后在空腹血糖、糖基化血红蛋白、尿β2微球蛋白、尿白蛋白排泄率以及血液流变学、血脂相关指标方面的变化,同时对比两组患者在临床疗效方面的差异。结果:治疗后,观察组患者空腹血糖为(6.1±0.5)mmol/L、糖基化血红蛋白为(6.5%±0.2%)、尿β2微球蛋白为(0.2±0.1)μg/L、尿白蛋白排泄率为(36.1±5.2)μg/min,均明显低于对照组(P<0.05);治疗后,观察组患者血浆黏度为(1.6±0.2)mpa/s,纤维蛋白原为(3.6±0.5)g/L、胆固醇为(8.1±0.6)mmol/L、甘油三酯为(2.6±0.2)mmol/L,均明显低于对照组(P<0.05);观察组患者临床治疗总有效率为95.00%(38/40),显著高于对照组(P<0.05)。结论:黄芪穴位注射液联合疏血通注射液对早期糖尿病肾病的疗效确切,通过改善患者血流动力学相关指标、降低血脂、控制蛋白尿,配合综合护理干预可巩固疗效。
OBJECTIVE: To analyze and observe the clinical efficacy and nursing measures of Astragalus injection combined with Shuxuetong injection in the treatment of early diabetic nephropathy. Methods: Totally 80 patients with early diabetic nephropathy admitted to our hospital from December 2014 to December 2015 were enrolled in this study. Patients were divided into two groups according to the parity of admission number. Forty patients were included in the control group and observed Group. The patients in the control group were treated with conventional western medicine. The patients in the observation group were treated with astragalus injection and Shuxuetong injection on the basis of the control group. The changes of fasting blood glucose, glycosylated hemoglobin, urinary β2-microglobulin, urinary albumin excretion rate, hemorrheology, and blood-lipid-related indexes before and after treatment were compared between the two groups. At the same time, the clinical efficacy of the two groups were compared The difference. Results: After treatment, fasting blood glucose was (6.1 ± 0.5) mmol / L, glycosylated hemoglobin was (6.5% ± 0.2%), urinary β2 microglobulin was (0.2 ± 0.1) μg / The protein excretion rate was (36.1 ± 5.2) μg / min and significantly lower than that of the control group (P <0.05). After treatment, the plasma viscosity of the observation group was (1.6 ± 0.2) mpa / s and that of fibrinogen was (8.1 ± 0.6) mmol / L for cholesterol and (2.6 ± 0.2) mmol / L for triglycerides were significantly lower than those in control group (P <0.05). The total effective rate of clinical treatment in observation group 95.00% (38/40), which was significantly higher than that of the control group (P <0.05). Conclusion: Astragalus acupoint injection combined with Shuxuetong Injection is effective in treating diabetic nephropathy in early stage. It can improve the hemodynamics index, lower the blood lipid and control the proteinuria, and consolidate the curative effect with the comprehensive nursing intervention.