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目的对比分析普食碘盐前、后1 31 I治疗甲亢的疗效 ,了解碘盐对1 31 I治疗甲亢的疗效有无影响。方法对 4 0 0例甲亢患者 ,其中普食碘盐前 (简称碘前组 ) 16 3例 ,碘盐后 (简称碘后组 ) 2 37例 ,按相同的公式计算1 31 I治疗量并判断、比较疗效。结果碘后组 6h、2 4h摄1 31 I率和 6h与 2 4h1 31 I率的比值及高峰前移率较碘前组显著下降 (P <0 0 5 ) ,而碘后组1 31 I治疗用量则显著大于碘前组 (P <0 0 1) ,但两组间每克甲状腺1 31 I用量差异无显著意义 (P >0 0 5 ) ;两组间治愈率、好转率、有效率、复发率、晚发甲减率差异均无显著意义 (P >0 0 5 )。结论碘盐并不影响1 31 I治疗甲亢的疗效 ,以甲状腺最高摄1 31 I率和计划每克甲状腺实际摄取1 31 I量计算治疗量是适当的
Objective To compare and analyze the therapeutic effect of 131I treatment on hyperthyroidism before and after treatment with iodized salt, and to find out whether iodized salt has any effect on the efficacy of 131I treatment of hyperthyroidism. Methods One hundred and forty patients with hyperthyroidism were enrolled in this study. Among them, 163 cases were pre-iodized salt (referred to as iodine pre-salt group) and 277 cases were treated with iodized salt (iodine-only group) , More effective. Results The ratio of iodine at 6h and 24h and the rate of peak at 4h and 31h at 6h and 24h were significantly lower than those at iodine group (P <0.05), while those at 131I after iodine group (P <0.01). However, there was no significant difference in the amount of 131 I application per gram of thyroid between the two groups (P> 0.05). The cure rate, improvement rate, effective rate, Recurrence rate, late hypothyroidism rate difference was not significant (P> 0.05). Conclusions Iodized salt does not affect the efficacy of 131 I in the treatment of hyperthyroidism. It is appropriate to calculate the amount of treatment based on the highest thyroid uptake of 131 I and the planned actual uptake of 131 I per gram of thyroid