论文部分内容阅读
目的观察血清降钙素原监测在儿科严重感染的变化特点。方法选取医院2013年8月-2014年8月收治的患儿126例,按患儿感染程度分为非感染组、轻度感染组以及重度感染组各42例。检测3组患儿白细胞(WBC)计数、C反应蛋白(CRP)以及血清降钙素原(PCT)指标。结果新生儿PCT和CRP重度感染组均高于轻度感染组高于非感染组患儿(P<0.05);WBC计数仅重度感染组高于非感染组(P<0.05)。在所监测的指标中,PCT的阴性、阳性预测值和敏感度、约登指数相对最高。结论 PCT检测在对儿科的感染程度的评估以及治疗中发挥着重要的作用,值得推广并应用。
Objective To observe the changes of serum procalcitonin in severe pediatric infection. Methods Totally 126 children admitted to our hospital from August 2013 to August 2014 were divided into non-infection group, mild infection group and severe infection group according to the degree of infection in children. The WBC count, C-reactive protein (CRP) and serum procalcitonin (PCT) were measured in 3 groups. Results The levels of PCT and CRP in neonates were significantly higher than those in mild infection groups (P <0.05). WBC count was higher in severe infection group than in non-infected group (P <0.05). Among the monitored indicators, PCT negative, positive predictive value and sensitivity, Youden index is the highest relative. Conclusion PCT test plays an important role in the evaluation and treatment of pediatric infection, which is worth popularizing and applying.