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目的:探讨小剂量多巴胺治疗新生儿窒息后喂养不耐受的临床疗效。方法:将72例窒息后喂养不耐受的新生儿随机分为对照组(n=35)和治疗组(n=37),对照组新生儿给予积极常规治疗,治疗组新生儿在常规治疗基础上给予小剂量多巴胺2～3μg.kg-1.min-1,以静脉输液泵静脉注射,观察治疗组与对照组新生儿胃肠功能恢复情况。结果:对照组与治疗组呕吐、腹胀及胃潴留消失时间,奶量达100 ml.kg-1.d-1所需的时间比较差异均有统计学意义(P<0.05)。结论:小剂量多巴胺治疗窒息后喂养不耐受新生儿有较好的疗效。
Objective: To investigate the clinical efficacy of low-dose dopamine in feeding intolerance after neonatal asphyxia. Methods: Seventy-two neonates with intolerance after asphyxia were randomly divided into control group (n = 35) and treatment group (n = 37). The neonates in the control group were given routine active treatment. On the small dose of dopamine 2 ~ 3μg.kg-1.min-1, intravenous infusion of intravenous infusion pump to observe the treatment group and control group of neonatal gastrointestinal function recovery. Results: The vomiting, abdominal distension and disappearance of gastric retention in the control group and the treatment group were statistically significant (P <0.05), the time required for the milk to reach 100 ml.kg-1.d-1 was statistically significant. CONCLUSIONS: Small doses of dopamine have a better therapeutic effect on neonates with intolerance after asphyxia.