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完整的DMD cDNA克隆的成功及应用,使人们能在60～70％的DMD及BMD患者中检测到基因的部分缺失。特异DNA顺序的扩增技术(PCR)、脉冲场电泳技术均已应用于该病的基因诊断。DMD蛋白也已分离鉴定,并用于这一遗传病的诊断。
The success and application of a complete DMD cDNA clone allows one to detect partial gene deletion in 60-70% of DMD and BMD patients. Specific DNA sequence amplification (PCR), pulsed-field electrophoresis have been used in the gene diagnosis of the disease. DMD protein has also been identified and used for the diagnosis of this genetic disease.