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目的 :雌、孕激素受体在围绝经期出血中的表达 ,与临床治疗的关系。方法 :免疫组化sp法ER、PR雌孕激素受体的观察。结果 :3 5 4例围绝经期出血的主要病理分型分别是单纯性增生、复杂性增生即占绝经期的 5 0 85 %,功能性内膜占 19 77%,恶性肿瘤占 2 82 %萎缩性内膜占 9 60 %,其他占 16 96%,雌孕激素受体在围绝经期出血的内膜中治疗阳性反应无显著差异。结论 :雌孕激素受体在围绝经期出血方面的表达有一定的意义 ,而病理分型对治疗有较重要的指异意义
Objective: The expression of estrogen and progesterone receptor in perimenopausal hemorrhage and its relationship with clinical treatment. Methods: The estrogen and progesterone receptor of ER and PR were detected by immunohistochemical SP method. Results: The main pathological types of the peri-menopausal bleeding in 3 54 cases were simple hyperplasia, complex hyperplasia accounting for 50 85% of menopause, functional endometrium 19 77%, malignant neoplasm accounting for 82% of atrophy Endometrial accounted for 9 60%, the other accounted for 16 96%, estrogen and progesterone receptor in the peri-menopausal bleeding in the treatment of endometrial no significant difference in positive reactions. Conclusion: The expression of estrogen and progesterone receptors in perimenopausal patients with hemorrhage has certain significance, while the pathological typing is more important for the treatment of different meaning