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用生物化学和组织学方法阐明小柴胡汤、桂枝茯苓丸、补中益气汤、红参单独用药和联合用药,对硫乙酰胺诱导大鼠肝硬变的抑制作用。 方法:选用3周龄Wistar大鼠,硫乙酰胺溶于水后拌入颗粒饲料,调至每日进药量为100mg/kg。将大鼠分为8组,分别喂饲正常或含硫乙酰胺饲料,同量加眼或不加服上述中药。小柴胡汤、桂枝茯苓丸和补中益气汤提取剂按1g/kg体重给药,红参的剂量为
The biochemical and histological methods were used to elucidate the inhibitory effect of Xiao Chaihu Decoction, Guizhi Fuling Pill, Buzhong Yiqi Decoction, and red ginseng alone and in combination on the inhibition of thioacetamide-induced liver cirrhosis in rats. METHODS: Three-week-old Wistar rats were used. After thioacetamide was dissolved in water, the pellets were mixed and adjusted to a daily dose of 100 mg/kg. The rats were divided into 8 groups and were fed with normal or thioacetamide-containing feeds respectively. The Xiaochaihu Decoction, Guizhi Fuling Pill, and Buzhong Yiqi Decoction extract were administered at 1g/kg body weight. The dose of red ginseng was