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关于男性老年人垂体和性腺的改变已有不少文献,但是究竟这些变化开始出现的年龄是多少岁,以及垂体和性腺两者之间的支配和反馈关系如何,目前资料不多。作者针对此问题作了临床研究和动物实验。作者将苏联医学科学院老年医学研究所临床部的280名住院男性,每5岁分为一组,40岁以下者都归入20—39岁组内,共分为11个年龄组,年龄范围为20—105岁。用放射免疫药箱法测定其血中睾丸酮、孕酮、雌二醇、卵泡刺激素(FSH)黄体生成素(LH),结果发现随着年龄的增大,上述5种激素均有明显的规律性的变化。如以20—39岁为比较的基线标准,随年龄的增大,睾丸酮逐渐减少,孕酮和雄二醇逐渐增多,LH和FSH亦逐
Much literature has been published on the changes of the pituitary gland and gonad in males, but at the moment how many years these changes begin to appear and the relationship between pituitary and gonadal domination and feedback. The author made a clinical study and animal experiments on this issue. The authors divided the 280 hospitalized men in the clinical department of the Institute of Geriatrics at the Soviet Academy of Medical Sciences into groups of 5 years and those under 40 years of age into the 20-39 age group and were divided into 11 age groups with an age range of 20-105 years old. The contents of testosterone, progesterone, estradiol and follicle-stimulating hormone (LH) in blood were determined by radioimmunity kit. The results showed that the above five hormones had obvious regularity Sexual changes. Such as 20-39 years old as the baseline for comparison, with age, testosterone gradually decreased, progesterone and androgynity gradually increased, LH and FSH also by