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目的：对氧自由基（ＯＦＲ）在高压氧（ＮＢＯ）引致氧惊厥发生过程中的作用及其机理作初步探讨。方法：１０５只ＳＤ雄性大鼠被随机分为常压空气组、高压常氧氮组、ＨＢＯ组、ＶｉｔＣ－ＨＢＯ组、ＶｉｔＥ－ＨＢＯ组、ＳＯＤ－ＨＢＯ组、ＨＢＯ惊厥组、ＶｉｔＣ－ＨＢＯ惊厥组、ＶｉｔＥ－ＨＢＯ惊厥组和ＳＯＤ－ＨＢＯ惊厥组共１０个组。进舱前ＶｉｔＣ－ＨＢＯ组、ＶｉｔＥ－ＨＢＯ组、ＳＯＤ－ＨＢＯ组、ＶｉｔＣ－ＨＢＯ惊厥组、ＶｉｔＥ－ＨＢＯ惊厥组和ＳＯＤ－ＨＢＯ惊厥组大鼠分别于腹腔内注射ＶｉｔＣ１００ｍｇ／ｋｇ，ＶｉｔＥ１００ｍｇ／ｋｇ或ＳＯＤ１万Ｕ／ｋｇ，其它动物被注入等量生理盐水。然后常压空气组动物置于舱内用空气持续通风２０分钟后出舱；其余各组暴露压力均为６００ｋＰａ（６ＡＴＡ）。高压常氧氮织动物暴露在含氧４％的氮氧混合气中，ＨＢＯ组、ＶｉｔＣ－ＨＢＯ组、ＶｉｔＥ－ＨＢＯ组、ＳＯＤ－ＨＢＯ组的动物则暴露在纯氧中分别停留２０分钟后减压；而ＨＢＯ惊厥组、ＶｉｔＣ－ＨＢＯ惊厥组、ＶｉｔＥ－ＨＢＯ惊厥组和ＳＯＤ－ＨＢＯ惊厥组动物则在高压下停留至有惊厥大发作后开始减压。减压采用匀速减压法，以１０分钟减至常压。采用电子自旋共振（ＥＳＲ）技术?
OBJECTIVE: To investigate the role of OFR in the pathogenesis of oxygen convulsion induced by hyperbaric oxygen (NBO) and its mechanism. Methods: 105 male Sprague-Dawley rats were randomly divided into normal pressure air group, high pressure normoxia group, HBO group, VitC-HBO group, VitE-HBO group, SOD-HBO group, HBO convulsion group and VitC-HBO convulsion group , VitE-HBO convulsion group and SOD-HBO convulsion group a total of 10 groups. The rats in VitC-HBO group, VitE-HBO group, SOD-HBO group, VitC-HBO convulsion group, VitE-HBO convulsion group and SOD-HBO convulsion group were injected with VitC100mg / SOD1 U / kg, other animals were injected with the same amount of saline. Atmospheric air grouping animals were then placed in the cabin with air and ventilated for 20 minutes before leaving the cabin. The exposure pressure of the other groups was 600 kPa (6ATA). The animals in the HBO group, the VitC-HBO group, the VitE-HBO group and the SOD-HBO group were exposed to pure oxygen for 20 minutes and then reduced While the animals in HBO convulsion group, VitC-HBO convulsion group, VitE-HBO convulsion group and SOD-HBO convulsion group stayed at high pressure and began to depressurize after the onset of seizures. Decompression using uniform decompression method to 10 minutes reduced to atmospheric pressure. Electronic spin resonance (ESR) technology?