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硫酸阿托品按10～20微克/公斤体重口服,常作为许多麻醉前常规用药。1.5～2毫克/公斤体重的大剂量给予可用于精神病治疗。文献报道对于儿童及一些发热病剂量小至2毫克而引起死亡的病例,亦有报道。 本文报道三个住院儿童施行了五官科小手术,术前用异丁嗪3毫克/公斤体重及硫酸阿托品口服。阿托品配制成每5毫升内含0.3毫克的溶液;但给患儿服后才发现5毫升内含有阿托品290毫克,患儿实际服用量分别为580、580、430毫克。服后1小时内安静,表现熟睡。后有四肢肌小痉挛、凝视和幻视,瞳孔显著散大,皮肤潮红,心动过速,无发绀,气道通畅,咽喉反射存在,给予观察及监护。考虑没有阿托品
Atropine sulfate at 10 ~ 20 ug / kg body weight oral, often as many conventional anesthesia medication. High doses of 1.5-2 mg / kg body weight can be used for psychiatric treatment. Reported in the literature for children and some febrile illness dose as small as 2 mg caused the death of the cases have also been reported. This article reports that three hospitalized children underwent minor surgery ENT, preoperative with isopuraline 3 mg / kg body weight and oral administration of atropine sulfate. Atropine is formulated to contain 0.3 mg per 5 ml solution; however, only 5 ml of 290 mg of atropine is found in children’s clothes after taking the supplement. The actual doses for children are 580, 580 and 430 mg respectively. Within 1 hour after serving quiet, performance asleep. After limb muscle spasms, staring and visual hallucinations, pupils significantly larger, the skin flushing, tachycardia, cyanosis, airway patency, the presence of throat reflex, giving observation and custody. Consider no atropine