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本文以四种实验性心律失常动物模型研究了Lorcainide抗心律失常的作用。静脉注射Lorcainide 2.5mg/kg,能明显提高猫静注地高辛(0.05mg/ml)中毒引起室性心律失常至死亡的剂量(P<0.05);亦能缩短家兔静注氯化钡2～4 mg/kg所致心律失常的持续时间(P<0.05);尚可减弱或消除家兔静注肾上腺素50μg/kg后引起多种心
In this paper, four experimental arrhythmia animal models of anti-arrhythmia Lorcainide. Intravenous injection of Lorcainide 2.5mg / kg, can significantly increase cats intravenous digoxin (0.05mg / ml) poisoning caused by ventricular arrhythmia to death dose (P <0.05); also shorten the intravenous injection of barium chloride 2 ~ 4 mg / kg duration of arrhythmia (P <0.05); still can reduce or eliminate the intravenous injection of epinephrine 50μg / kg caused a variety of heart