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目的:探讨经尿道前列腺电切术联合间断雄激素阻断治疗前列腺癌的临床疗效。方法:回顾分析我院为24例确诊为合并膀胱出口梗阻晚期前列腺癌患者行经尿道前列腺等离子汽化加全间断雄激素阻断术的临床资料。结果:24例手术均获成功,术中出血少,术后随访12个月,术后3个月国际前列腺症状评分(7.12±4.24),生活质量评分(1.8±0.4),残余尿(26.5±12.2)ml,最大尿流率(17.82±2.78)ml/s,血清PSA平均(6.3±2.1)ng/ml。结论:等离子汽化电切加间断雄激素阻断治疗能提高合并膀胱出口梗阻晚期前列腺癌患者的生存质量。
Objective: To investigate the clinical efficacy of transurethral resection of prostate combined with intermittent androgen blockade in the treatment of prostate cancer. Methods: A retrospective analysis of our hospital for 24 cases of diagnosed as advanced bladder outlet obstruction in patients with advanced prostate cancer by transurethral vaporization of plasma plus full-androgen blockade of clinical data. Results: All the 24 surgeries were successful, less bleeding during operation, 12 months postoperative follow-up, 7.12 ± 4.24 3 months postoperation, 1.8 ± 0.4 quality of life score, 26.5 ± 12.2) ml, the maximal uroflow rate was (17.82 ± 2.78) ml / s and the average serum PSA was (6.3 ± 2.1) ng / ml. Conclusion: Plasma-assisted electrovaporization plus intermittent androgen blockade therapy can improve the quality of life of advanced prostate cancer patients with bladder outlet obstruction.