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ＨＩＶ 的侵入与宿主细胞表面共受体ＣＣＲ５ 密切相关。本文报道了ＣＣＲ５ ５端非编码区多态性的研究，以及用基因删除，点突变等方法研究ＣＣＲ５ Ｎ 端和Ｃ端的功能区域。发现了ＣＣＲ５ Δ３２ 受体基因缺陷型能有保护人群免受ＨＩＶ 的感染。
The invasion of HIV is closely related to the host cell surface CCR5. In this paper, we report the research on the polymorphism of CCR5 5 non-coding region and the functional regions of N-terminal and C-terminal of CCR5 by gene deletion and point mutation. Found CCR5 Δ32 receptor gene deficiency can protect the population from HIV infection.