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急性冠状动脉综合征(acute coronary syn-drome,ACS)包括不稳定型心绞痛、ST段抬高心肌梗死和非ST段抬高心肌梗死,是以冠状动脉粥样硬化斑块破裂或侵蚀,继发完全或不完全闭塞性血栓形成是病理基础的一组临床综合征。ACS是冠心病病程中的严重事件,往往导致大面积心肌梗死甚至猝死,因此早期诊断对于及时治疗防止心肌进一步缺血坏死非常重要。近年来研究发现缺血修饰白蛋白(Ischemia modified albumin,IMA)在心肌缺血发生后5～10 min可迅速升高,成为一项早期诊断心肌缺血的生化标志物。
Acute coronary syn-drome (ACS), including unstable angina pectoris, ST elevation myocardial infarction and non-ST elevation myocardial infarction, is based on the rupture or erosion of coronary atherosclerotic plaques and secondary Complete or incomplete occlusive thrombosis is a pathological basis for a group of clinical syndromes. ACS is a serious event in the course of coronary heart disease, often leading to a large area of myocardial infarction or even sudden death, so early diagnosis is very important for the timely treatment to prevent myocardial ischemic necrosis. In recent years, studies have found that Ischemia modified albumin (IMA) can rapidly increase after 5 ~ 10 min after myocardial ischemia and become an early biochemical marker of myocardial ischemia.