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目的:探讨子宫肌瘤剔除术后复发的相关因素,为临床降低复发率提供科学依据和有效途径。方法:收集2002年1月至2010年12月北京市怀柔区第一医院妇科门诊收治的445例子宫肌瘤剔除术患者的临床资料及子宫肌瘤术后复发随访情况,对相关因素进行单因素和多因素logistic分析。结果:随访的445例患者复发94例,复发率为21.12%,复发距手术时间6～96个月,平均(38.5±12.8)个月。年龄、BMI、肌瘤数目、肌瘤大小、肌瘤部位、既往分娩史、术后用药与肌瘤复发显著相关,其中年龄、BMI、肌瘤数目是子宫肌瘤复发的独立危险因素,术后妊娠是子宫肌瘤复发的保护因素。结论:年龄、BMI、肌瘤数目是子宫肌瘤复发的独立危险因素,术后妊娠是保护因素。
Objective: To explore the related factors of recurrence after myomectomy, to provide a scientific basis and an effective way to reduce the recurrence rate clinically. Methods: The clinical data of 445 cases of uterine fibroids removed from gynecology outpatient department of the First Affiliated Hospital of Huairou District, Beijing from January 2002 to December 2010 were retrospectively analyzed. The related factors were analyzed by single factor And multivariate logistic analysis. Results: A total of 445 patients were followed up for 94 cases. The recurrence rate was 21.12%. The recurrence time ranged from 6 to 96 months (mean, 38.5 ± 12.8 months). Age, BMI, number of fibroids, fibroids size, fibroids location, history of previous deliveries and postoperative medication were significantly correlated with fibroids recurrence. Age, BMI and fibroids numbers were independent risk factors for recurrence of uterine fibroids. Pregnancy is a protective factor of recurrence of uterine fibroids. Conclusion: Age, BMI and myoma number are independent risk factors for recurrent uterine fibroids. Postoperative pregnancy is a protective factor.