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目的:观察口服消水方联合顺铂胸腔灌注治疗恶性胸腔积液的临床疗效。方法:118例恶性胸腔积液患者随机分为两组,治疗组65例采用口服中药消水方联合顺铂胸腔灌注,对照组53例单用顺铂胸腔灌注。以恶性胸腔积液的近期疗效、生活质量评分及临床症状积分为指标进行临床观察。结果:治疗组和对照组近期有效率分别为72.3%和66.1%,两组无显著性差异,但治疗组较对照组生活质量显著改善(P<0.05),症状明显缓解(P<0.05)。结论:消水方联合顺铂胸腔灌注治疗恶性胸腔积液,近期疗效未见明显提高,但可减轻症状,提高生活质量。
Objective: To observe the clinical curative effect of oral Xiao Shuifang combined with Cisplatin in the treatment of malignant pleural effusion. Methods: A total of 118 patients with malignant pleural effusion were randomly divided into two groups. 65 cases in the treatment group were treated with oral administration of traditional Chinese medicine and cisplatin, and 53 cases in the control group were treated with cisplatin alone. The clinical efficacy of malignant pleural effusion with the short-term efficacy, quality of life scores and clinical symptom scores as an indicator of clinical observation. Results: The effective rates of the treatment group and the control group were 72.3% and 66.1% respectively. There was no significant difference between the two groups. However, the quality of life of the treatment group was significantly improved (P <0.05) and the symptoms were relieved (P <0.05). Conclusion: Dihydrate combined cisplatin pleural perfusion in the treatment of malignant pleural effusion, no significant improvement in the recent efficacy, but can reduce symptoms and improve quality of life.