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目的:通过临床研究评价健脾理气散治疗儿童功能性消化不良的临床疗效。方法:将60例符合入选标准的功能性消化不良患儿随机分为治疗组、对照组各30例。治疗组给予自拟健脾理气散,对照组给予吗丁啉,疗程均为1个月,并分别检测治疗前后的胃半排空,记录患儿治疗前后的症状积分,进行比较。结果:治疗组总有效率为96.67%;对照组总有效率为80.00%,两组疗效存在显著差异(P<0.05)。治疗组治疗后症状、体征总积分低于对照组,差异有统计学意义(P<0.01);治疗组治疗后胃固体半排空时间与对照组比较无统计学意义(P>0.05)。结论:健脾理气散治疗儿童功能性消化不良具有较好的疗效,中药作用不局限于促胃肠动力,从这些角度健脾理气散值得进一步深入研究。
Objective: To evaluate the clinical effect of Jianpi Liqi on children with functional dyspepsia. Methods: Sixty children with functional dyspepsia who met the inclusion criteria were randomly divided into treatment group and control group with 30 cases each. Patients in the treatment group were treated with Jianpi Liqi Powder and control group with domperidone. The course of treatment was 1 month. The gastric emptying before and after treatment was detected. The symptom scores before and after treatment were recorded and compared. Results: The total effective rate in the treatment group was 96.67%. The total effective rate in the control group was 80.00%. There was significant difference between the two groups (P <0.05). After treatment, the total score of symptoms and signs in the treatment group was lower than that in the control group (P <0.01). The treatment time of gastric emptying in the treatment group was not significantly different from that in the control group (P> 0.05). Conclusion: Jianpi Liqi Powder has good curative effect in treating functional dyspepsia in children. The effect of traditional Chinese medicine is not limited to promoting gastrointestinal motility. From these angles, it is worth further studying.