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目的：分析新时期医学生心理健康状况及特点。方法采用90项症状自评量表（SCL‐90）对南京市某985高校2011—2013级1016名医学生（观察组）进行测评，并以该校570名建筑学院学生为对照组进行比较。结果观察组 SCL‐90测评总均分和阳性项目均分高于对照组（P＜0．05）。观察组在躯体化、强迫症状、人际关系敏感、忧郁、焦虑、敌对、恐怖、偏执、精神病性和其他项目10个因子测评分数均高于对照组（ P＜0．05）。观察组女生抑郁、焦虑和恐怖3个因子测评分数高于男生（P＜0．01）。观察组2011级、2012级和2013级医学生SCL‐90测评总分总体比较差异有统计学意义（ P＜0．05）。2011级医学生在人际关系敏感、抑郁、偏执3个因子测评分数高于2012级和2013级医学生（ P＜0．05）。结论医学生的心理健康现状堪忧，需根据医学生的心理健康状况特点，开展相应的心理辅导或治疗。“,”Objective To explore the mental health status and characteristics of present medical students .Methods The Symptom Checklist‐90(SCL‐90) was used to evaluate the mental health of 1016 medical students (group A ) from sophomore to senior in a 985‐level College of Nanjing .The results were compared to 570 students of architecture(group B) .Results The SCL‐90 total scores and the positive items scores in group A were significantly higher than those in group B(P<0 .05) .The scores of somatization ,force symptom ,interpersonal sensitivity ,depression ,anxiety ,hostility ,terror , paranoia ,psychosis and other projects in group A were also significantly higher than those in group B (P<0 .05) .The depression ,anxiety and terror scores of female students were higher than those in male students in group A (P<0 .01) .The SCL‐90 scores were significantly differenct among the students of 2011 ,2012 and 2013(P<0 .05) .The scores of sensitivity ,depression ,paranoid in medical students of 2011 were higher than those in those of 2012 and 2013(P<0 .05) .Conclusion The mental health status of present medical students is a worrying problem .On the basis of mental health characteristics of present medical students ,appropriate psychological guidance and treatment are needed .