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用Golgi-Cox镀染法对人工滴加阿托品于幼猫单、双眼引起的屈光参差和屈光不正性弱视猫模型,定量分析了其弱视眼支配的外膝体背核第Ⅰ,Ⅱ,Ⅲ类神经元的形态学变化。结果表明,这两种弱视眼支配的各类外膝体背核细胞无论细胞体还是树突均发生了不同程度的萎缩,这种变化以第Ⅱ类神经元和屈光参差性弱视猫更为显著。本研究为屈光参差和屈光不正性弱视发病机理的外周“废用”学说提供了形态解剖学支持。
The Golgi-Cox plating method was used to artificially add atropine to kittens, anisometropia caused by both eyes and ametropic amblyopia cat model, Morphological changes of neurons of type. The results showed that these two kinds of amblyopia eyes dominate the various types of dikadi cells of the dikapanese regardless of cell body or dendrites were varying degrees of atrophy, this change to class Ⅱ neurons and anisometropic amblyopia cat more Significant. This study provides morphometric anatomy support for the peripheral “disuse” doctrine of anisometropic and ametropic amblyopia pathogenesis.