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1、日本人的白塞氏病和HLA相关性 1)HLA-A、B及C抗原日本人的白塞氏病和HLA-B5密切相关。B5频率为61～88％,对照组健康人的频率为29—38％。分离抗原的研究表明,日本人白塞氏病与BW51呈高度相关。大野等报告,白塞氏病患者的BW51(B5)多来自母亲,且其发病危险率也明显高。此外,从白塞氏病患者双亲的HLA频率来看,母亲B5频率比较高,而父亲的B5频率与对照组相比没有差异,可见HLA与疾病的相关性,是倾向于双亲的一方,这可能是白塞氏病的
1, Behcet & apos; s Disease and HLA Correlation in Japanese 1) HLA-A, B and C antigens Behcet & apos; s disease in Japanese is closely related to HLA-B5. The frequency of B5 was 61-88%, while that of healthy people in control group was 29-38%. Studies on the isolation of antigens have shown that Behcet’s disease in Japanese is highly correlated with BW51. Ono and other reports, Behcet’s disease in patients with BW51 (B5) mostly from the mother, and the incidence of risk was also significantly higher. In addition, from the HLA frequency of parents of Behcet’s disease, mothers B5 frequency is relatively high, while the father’s B5 frequency is no difference compared with the control group, showing that HLA and disease, is the tendency of the parents of this It may be Behcet’s disease