论文部分内容阅读
目的总结鼻腔外侧壁切除术治疗鼻腔鼻窦腺样囊性癌的临床疗效,并复习文献探讨影响鼻腔鼻窦腺样囊性癌患者预后的因素。方法回顾性分析2000年1月-2011年7月6例鼻腔鼻窦腺样囊性癌患者的临床病理资料,全部采用鼻腔外侧壁切除术加术后放疗的方法,放疗结束后随访6个月～2年,并定期鼻内镜下清理术腔。结果随访期间术腔未见明显复发。由于随访时间短,失去患者的追踪观察,未能统计患者的复发率与生存率。复习文献中鼻腔鼻窦腺样囊性癌采用手术加放疗,5年生存率可达到70%左右,10年生存率可达到40%～50%左右,对复发患者仍然采用以手术治疗为主的综合治疗。结论手术加放疗的综合治疗是治疗鼻腔鼻窦腺样囊性癌的主要治疗方法,局部复发是导致鼻腔鼻窦腺样囊性癌治疗失败的主要原因,远处转移是影响患者预后的重要因素。
Objective To summarize the clinical efficacy of nasal lateral wall resection in the treatment of nasal sinus adenoid cystic carcinoma and review the literature to explore the factors that affect the prognosis of nasal sinus adenoid cystic carcinoma. Methods The clinical and pathological data of 6 patients with nasal sinus adenoid cystic carcinoma from January 2000 to July 2011 were retrospectively analyzed. All patients underwent resection of lateral nasal wall and postoperative radiotherapy. The patients were followed up for 6 months ~ 2 years, and regular endoscopic clear the surgical cavity. Results No significant recurrence of the surgical cavity during follow-up. Due to the short follow-up period, the patient’s follow-up observation was lost, and the recurrence rate and survival rate of the patients were not counted. Review literature nasal sinus adenoid cystic carcinoma with surgery and radiotherapy, 5-year survival rate can reach about 70%, 10-year survival rate can reach 40% to 50%, the recurrence of patients is still based on the use of surgical treatment-based treatment. Conclusions The combined operation of surgery and radiotherapy is the main treatment for nasal sinus adenoid cystic carcinoma. Local recurrence is the main reason for the failure of nasal sinus adenoid cystic carcinoma. The distant metastasis is an important factor affecting the prognosis of patients.