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目的:探讨肝硬化时对机体凝血系统的影响,了解参与凝血的各种因子的变化情况。方法:测定60例肝硬化患者和健康体检者50例,PLAT、PT、APTT、TT、FIB、D-二聚体六项指标综合分析。结果:肝硬化组与健康组各项指标对照均有统计学差异(P<0.01),肝硬化代偿组与失代偿组比较也存在统计学差异(P<0.01)。结论:肝硬化时对机体凝血系统和纤溶系统影响显著,且代偿期与失代偿期各项指标差异显著。
Objective: To investigate the influence of cirrhosis on the coagulation system of the body and to understand the changes of various factors involved in coagulation. Methods: Sixty patients with cirrhosis and 50 healthy people were examined. Six indicators of PLAT, PT, APTT, TT, FIB and D-dimer were analyzed comprehensively. Results: The indexes of cirrhosis and healthy group were statistically significant (P <0.01). There was also significant difference between decompensated group and decompensated group (P <0.01). Conclusion: The effect of cirrhosis on the coagulation system and fibrinolytic system is significant, and the indicators of decompensation and decompensation have significant differences.