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Guillain-Barre综合征(GBS)报告较多,但血清和脑脊液(CSF)中抗Epstein-Barr病毒(EBV)抗体价升高很少报告,作者报告1例。男性,55岁,某年1月始出现咳嗽、咯痰等感冒样症状,2月18日腰痛及四肢远端麻木与无力,22日上下肢无力,3月4日入院。查体:浅表淋巴结无异常。神经系统检查:上下肢近端肌力减弱,以下肢明显,髋、膝关节肌力3～3~+级;四肢远端呈手套袜套样感觉障碍,上肢痛温觉、下肢触温痛觉、位置觉减弱,振动觉普遍减弱。腱反射除二头肌腱外皆消失,病理反射(一),双侧Lasegue氏征阳性,指鼻试验轻度共济失调。眼底及颅神经正常。白血球9600/mm~3(异型淋巴细胞占2%),血沉75mm/小时,CRP+,α_2球蛋白升高等示中度炎症,r-GTP、BUN轻度升高;运动神经传导速度:左侧正中神经
There are more reports of Guillain-Barre syndrome (GBS), but there are few reports of elevated anti-Epstein-Barr virus (EBV) antibody in serum and cerebrospinal fluid (CSF). One case was reported by the authors. Male, 55 years old, a year in January began to cough, expectoration and other flu-like symptoms, February 18 low back pain and limbs numbness and weakness on the 22nd upper limb weakness, March 4 admission. Physical examination: superficial lymph nodes without exception. Nervous system examination: lower extremity proximal muscle weakness, obvious lower limbs, hip, knee muscle strength 3 ~ 3 ~ + level; distal limbs were gloves socks like sensory disturbance, upper limb pain temperature sensation, lower limb temperature sensation, location Feeling weakened, vibration generally weakened. Tendon reflex disappeared except biceps tendon, pathological reflexes (A), bilateral Lasegue’s sign positive, finger nose test mild ataxia. Fundus and cranial nerves normal. Moderate white blood cells showed a moderate increase of 9600 / mm 3 (2% atypical lymphocytes), 75 mm / hour of erythrocyte sedimentation rate, elevated CRP + and α 2 globulin, and slight increase of r-GTP and BUN; motor nerve conduction velocity: nerve