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目的探讨逆行自体血液预充技术(RAP)和鼓泡式氧合器联合应用对儿童体外循环的影响。方法 40例体外循环手术患儿,随机分为实验组(n=20)和对照组(n=20)。实验组联合应用逆行自体血液预充技术和鼓泡式氧合器,对照组单纯使用膜式氧合器。分别记录两组患者相关观察指标。结果两组患者年龄、体重、体表面积、体外循环时间、主动脉阻断时间差异无统计学意义(P>0.05)。实验组可减少预充液量,虽转前、转中、术后红细胞压积两组差异也无统计学意义(P>0.05),但实验组稍高于对照组。实验组呼吸机辅助时间、围术期临床用血量均少于对照组,差异有统计学意义(P<0.05)。结论逆行自体血液预充技术和鼓泡式氧合器联合应用可减少临床用血量,促进患儿术后恢复,降低手术费用。
Objective To investigate the effect of retrograde autologous blood prefilling (RAP) and bubble oxygenator on cardiopulmonary bypass in children. Methods Forty cases of children undergoing cardiopulmonary bypass were randomly divided into experimental group (n = 20) and control group (n = 20). The experimental group combined with retrograde autologous blood prefilled technology and bubble oxygenator, the control group simply use membrane oxygenator. Two groups of patients were recorded related indicators. Results There was no significant difference in age, body weight, body surface area, cardiopulmonary bypass time, and aortic cross-clamping time between the two groups (P> 0.05). Experimental group can reduce the amount of prefilled fluid, although before turning, during and after hematocrit differences were not statistically significant (P> 0.05), but the experimental group slightly higher than the control group. The experimental group ventilator-assisted time, perioperative clinical blood volume were less than the control group, the difference was statistically significant (P <0.05). Conclusion The combination of retrograde autologous blood prefilling and bubble oxygenator can reduce the amount of clinical blood supply, promote the recovery of children and reduce the cost of operation.