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作者比较在高、低脂肪饮食时美降脂(Lovastatin)的降脂效果。在三周内服用美降脂40mg/d或安慰剂,高胆固醇血症患者在代谢病房条件下接受规定饮食。于规定饮食的最后一周测定多种脂蛋白水平。19例完成高脂(43％千焦耳)饮食时的观察,16例完成低脂(25％千焦耳)饮食时的观察。同服安慰剂相比,在两种饮食条件下服美降脂使总胆固醇降低23％,使低密度脂蛋白降低30％,饮食和药物之间无显著的相互作用。在规定饮食下高密度脂蛋白胆固醇提高7～8％。美
The authors compared the lipid-lowering effect of Lovastatin with high and low fat diets. In the three weeks taking the United States lipid-lowering 40mg / d or placebo, hypercholesterolemia patients in the metabolic ward under the conditions of the prescribed diet. Multiple lipoprotein levels were determined during the last week of the prescribed diet. Nineteen completed the high-fat (43% of the jJ) diet and 16 completed the low-fat (25% of the jJ) diet. Compared to placebo, taking US diet in both dietary conditions reduced total cholesterol by 23%, reduced LDL by 30%, and no significant interaction between diet and medication. Under the provisions of diet high-density lipoprotein cholesterol increased by 7 to 8%. nice