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目的了解心率变异性与β受体过敏症之间的关系。方法应用Holter系统对已确诊的25例β受体过敏症患儿(观察组)进行动态心电图监测及心率变异性分析,对各种参数(包括时域指标及频域指标)进行分析,并与28例正常体检儿童(对照组)的心率变异性分析中的各项参数进行比较,了解两组参数之间的差异。结果观察组的时域指标中全部窦性心搏RR间期标准差(SDNN)、相邻NN之差>50 ms的个数占总窦性心搏个数的百分比(PNN50)、相邻RR间期差值的均方根(r MSSD)均有下降,观察组和对照组差异无统计学意义(P>0.05);频域指标中低频与高频的比率(LF/HF)升高,高频(HF)下降;低频(LF)、极低频(VLF)和对照组比较差异无统计学意义(P>0.05)。结论β受体过敏症患儿存在植物神经调节失衡现象,表现为交感神经张力正常,迷走神经张力下降。
Objective To understand the relationship between heart rate variability and β-receptor hypersensitivity. Methods Holter system was used to analyze the dynamic electrocardiogram (ECG) and heart rate variability (HRV) of 25 confirmed β-receptor hypersensitivity children (observation group), and to analyze various parameters (including time domain index and frequency domain index) 28 normal subjects (control group) heart rate variability analysis of the parameters were compared to understand the differences between the two groups of parameters. Results In the time domain of the observation group, the standard deviation of all RRs (SDNN), the difference between adjacent NNs> 50 ms as a percentage of the total number of sinus beats (PNN50), the difference between adjacent RR intervals (RMSSD) of observation group and control group had no significant difference (P> 0.05); the ratio of low frequency to high frequency (LF / HF) in high frequency (HF / HF) ). There was no significant difference between low frequency (LF), very low frequency (VLF) and control group (P> 0.05). Conclusion There is an imbalance of autonomic regulation in children with β-receptor hypersensitivity, which shows normal sympathetic tone and decreased vagal tone.