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目的探讨适合血吸虫病疫情控制地区的查病方案。方法选择江滩型血吸虫病流行区的扬州市邗江区沿江村6~65岁人群作为查病对象,按照单盲试验的原则,同时用DDIA+Kato-Katz法、DDIA+集卵孵化法、ELISA+Kato-Katz法和ELISA+集卵孵化法4种查病方案进行查病,分析病人漏检原因,比较各种查病方案的漏检率和查病费用。结果对1251人进行了查病,受检率为92.19%,共查出血清学阳性298例,粪检阳性29例。其中DDIA+Kato-Katz法、DDIA+集卵孵化法、ELISA+Kato-Katz法和ELISA+集卵孵化法4种查病方案分别查出粪检阳性病人19、26、19例和24例,分别漏检10、3、10例和5例,漏检率分别为34.48%、10.34%、34.48%和17.24%;4种方案人均查病费用分别为6.83、7.06、7.33元和7.62元。DDIA、ELISA筛查时分别漏检病人1例和2例;Kato-Katz、集卵孵化法分别漏检病人9例和3例,漏检率为31.03%和10.34%。结论DDIA+集卵孵化法或ELISA+集卵孵化法均可作为血吸虫病疫情控制地区的查病方案,但DDIA+集卵孵化法更有效、经济。
Objective To investigate the disease-control program for schistosomiasis control. Methods According to the principle of single-blind test, DD61 + Kato-Katz method, DDIA + egg hatching method and ELISA + ELISA were used to investigate the prevalence of schistosoma japonicum endemic schistosomiasis in Yanjiang Village, Kato-Katz method and ELISA + egg hatching method were used to check the disease. The cause of missed test was analyzed, and the missed detection rate and the cost of disease check were compared. Results A total of 1251 people were examined, the detection rate was 92.19%. A total of 298 serological positive tests and 29 stool tests were found. DDH + Kato-Katz method, DDIA + egg hatching method, ELISA + Kato-Katz method and ELISA + egg hatching method were used to detect 19, 26, 19 and 24 cases of stool positive patients respectively, The detection rate was 34.48%, 10.34%, 34.48% and 17.24% respectively in 10, 3, 10 and 5 cases. The cost of disease-seeking per person in each of the 4 protocols was 6.83, 7.06, 7.33 yuan and 7.62 yuan respectively. One case and two cases were missed by DDIA and ELISA screening, respectively. Kato-Katz and egg-hatching methods missed 9 cases and 3 cases respectively. The missed detection rate was 31.03% and 10.34% respectively. Conclusion DDIA + egg hatching method or ELISA + egg hatching method can be used as a check-up program for the control of schistosomiasis outbreak. However, DDIA + egg hatching method is more effective and economical.