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引产是现代产科处理中的重要手段之一.米索前列醇为前列腺素E_1的类似物,近年来国外用于足月妊娠引产已有较多报道.本研究通过随机对照,分别应用米索前列醇和人工破膜加催产素引产进行临床效果比较,并对母、婴的安全性进行观察.1 资料与方法1.1 病例选择 对我院1997年5～11月住院期间因各种指征如过期妊娠、预防过期妊娠、妊高征需引产终止妊娠的孕妇100名,随机分成两组,米索前列醇组和人工破膜加催产素组,各50名,两组对象均为初产妇,年龄(21～31)y,孕周(39~+～42~(+1)wk),宫颈Bishop评分7～9分,未临产,无胎膜早破、产前出血、胎位异常、头盘不对称、胎儿宫内窘迫、多胎妊娠及疤痕子宫.
Induction of labor is one of the important means of modern obstetric treatment.Mixoprost is prostaglandin E_1 analogue, in recent years abroad for full-term pregnancy induction has been more reported.In this study, by randomized controlled trials, respectively, misoprostol Alcohol and artificial rupture of membranes and oxytocin induction of labor to compare the clinical efficacy and safety of the mother and infant were observed.1 Materials and Methods 1.1 Case Selection Hospital of our hospital from May to November 1997 due to various indications such as obesity , To prevent the outdated pregnancy, pregnancy induced hypertension syndrome termination of pregnancy induced termination of pregnancy 100, were randomly divided into two groups, misoprostol group and artificial rupture of membranes and oxytocin group, 50, the two groups of objects are primipara, age ( 21 ~ 31) y, gestational age (39 ~ + ~ 42 ~ (+1) wk), cervical Bishop score of 7 to 9, no labor, no premature rupture of membranes, prenatal bleeding, abnormal fetal position, , Fetal distress, multiple pregnancies and scarring of the uterus.