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采用Nicolet－viking－Ⅱ电生理诊断仪对28例橄榄—桥脑—小脑萎缩（OPCA）患者及19例健康志愿者行双侧肢体体感诱发电位（SEP）检查，结果表明：OPCA组正中神经N20潜伏期延长，N20及P23波幅减低，与对照组相比差异有显著性意义（P＜0．05）；中枢传导时间（N13—N20，经协变量校正后）明显延长（P＜0．05），其中N20波缺失1例，均为双侧性；腕部至Erb’s神经传导速度（CVI）及N9、N11、N13潜伏期均正常。左侧N20、右侧P23及胜后神经诱发电位P37潜伏期与对照组相比差异均有显著性意义（P＜0．05），经协变量校正后显示N21、N45潜伏期明显延长（P＜0．05）；而中枢传导时间N21—P37及周围神经的监护电位（PF）均无差异（P＞O．05）；内踝至皮层传导速度（CVZ）减慢，两组相比，差异具有极为显著意义（P＜0．01）；有8例P37波缺失（其中R侧6例，一侧性2例），占28．5％。上述结果提示OPCA患者除了有中枢传导障碍外，可能同时有周围神经传导障碍。
28 cases of olivopontocerebellar atrophy (OPCA) patients and 19 healthy volunteers were examined by Nicolet-viking-Ⅱ electrophysiological examination. The results showed that: the positive nerve N20 (P <0.05). The conduction time of central nervous system (N13-N20, corrected by covariate) was significantly prolonged (P <0.05), and the latency of N20 and P23 decreased. Compared with the control group, , Of which N20 wave was absent in 1 case, both of which were bilateral. The CVI and N9, N11 and N13 latency from the wrist to Erb’s nerve center were all normal. There were significant differences between the left N20, the right P23 and the post-v. P37 latent phase compared with the control group (P <0.05). After covariate calibration, the latency of N21 and N45 was significantly prolonged .05). There was no difference in central conduction time between N21-P37 and PF (P> 0.05), while the medial malleolus to cortical conduction velocity (CVZ) slowed down. There was a significant difference between the two groups (P <0.01). There were 8 cases of P37 wave deletion (including 6 cases on R side and 2 cases on one side), accounting for 28.5%. The above results suggest that in addition to OPCA patients with central conduction disorders, peripheral nerve conduction disorder may also have both.