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报道了采用硫代活性酯法合成头孢唑啉(1)的新方法·即先将1H-四唑乙酸(2)与2-甲基-1·3,4-噻二唑-5-硫醇(3)以二环己基碳二亚胺(DCC)为缩合
Reported a new method for the synthesis of cefazolin (1) by the thio-active ester method, that is 1H-tetrazoleacetic acid (2) and 2-methyl-1,3,4-thiadiazole- (3) to dicyclohexylcarbodiimide (DCC) for condensation