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目的探讨“O”型孕妇产前血清IgG抗-A(B)进行吸收试验后抗体效价检测的意义,监测它与新生儿溶血病之间的关系。方法对13例“O”型孕妇在孕36周血清IgG抗-A(B)进行检测,再对血清分别用A、B细胞进行吸收试验,排除IgG抗-AB干扰,检测吸收后IgG抗-A(B)效价。结果孕妇产前血清吸收后IgG抗-A/B抗体效价更能准确预测新生儿溶血病的发生。结论产前对ABO血型不合的夫妇进行检测,尤其对“O”型孕妇血清吸收试验后IgG抗-A(B)效价的检测,对进一步准确判断、预防和治疗新生儿溶血病有重要的临床意义。
Objective To investigate the significance of detecting antibody titer after prenatal serum IgG anti-A (B) of “O” type pregnant women undergoes absorption test and monitor its relationship with hemolytic disease of newborn. Methods Thirteen “O” type pregnant women were tested for serum IgG anti-A (B) at 36 weeks’ gestation. Absorption tests on serums were performed on A and B cells, respectively, and IgG anti-AB interference was excluded. Anti-A (B) titer. Results The IgG anti-A / B antibody titer after prenatal serum absorption in pregnant women can predict the occurrence of hemolytic disease in neonates more accurately. Conclusion Prenatal detection of ABO-incompatible couples, especially for the detection of IgG anti-A (B) titer after serum absorption test of “O” type pregnant women, is of great value for further accurate judgment, prevention and treatment of neonatal hemolytic disease Important clinical significance.