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背景:目前有较多测量骨矿含量的方法,但不同的方法所反映的测量部位、临床应用价值及对正常人群同骨质疏松症的鉴别能力有所不同。目的:观察深圳地区妇女腰椎骨矿含量,建立正常骨矿含量定量CT标准,为临床预防及指导治疗该地区骨质疏松提供依据。设计:以正常妇女为研究对象,随机化同期对照,观察对比研究。单位:一所区级医院医学影像科。对象:选择2000-09/2002-03本深圳市龙岗区中心医院的体检深圳地区妇女120例为研究对象,年龄30～69岁。将研究对象分成30～39,40～49,50～59,60～69岁4个年龄组,每组30例。方法:利用定量CT软件测量研究对象的骨矿质含量,从而确定深圳地区妇女骨矿质含量标准,并与其他地区妇女的骨矿质含量进行对照分析。主要观察指标:观察深圳地区妇女骨矿质含量平均值,并与国内外其他地区进行比较。结果:定量CT测量结果与灰重呈直线相关,并可用如下直线回归方程表示:灰重=0.92432×骨矿含量+39.0633。深圳地区绝经期前后妇女各年龄组腰椎骨矿含量丢失率逐渐增加,松质骨、密质骨平均年丢失率1.38%,0.84%。深圳地区50～59组妇女骨矿含量(135.31±18.36)mg/cm3明显高于长春地区、北京地区、美国妇女(20.21±37.40),(116.7±26.6),(119.5±27.1)mg/cm3(t=2.002,3.383,3.636,P<0.05～0.01);深?
Background: There are many methods to measure the bone mineral content at present, but different methods reflect the measurement site, clinical application value and ability to distinguish osteoporosis from normal people. OBJECTIVE: To observe the lumbar bone mineral content of women in Shenzhen and to establish the quantitative CT criteria for normal bone mineral content, so as to provide the basis for clinical prevention and treatment of osteoporosis in this area. Design: The normal women as the research object, randomized the same period control, observe the comparative study. Unit: a district-level hospital medical imaging department. PARTICIPANTS: 120 women aged from 30 to 69 years were selected as the study subjects in Shenzhen City, Longgang District Central Hospital from September 2000 to March 2002. Subjects were divided into three age groups of 30 ~ 39, 40 ~ 49, 50 ~ 59 and 60 ~ 69 years old, 30 cases in each group. Methods: Quantitative CT software was used to measure the bone mineral content of the study subjects to determine the bone mineral content of women in Shenzhen, and compared with the bone mineral content of women in other regions. MAIN OUTCOME MEASURES: The average bone mineral content of women in Shenzhen was observed and compared with other regions at home and abroad. Results: Quantitative CT measurements were linearly correlated with ash weight and can be expressed as a linear regression equation as follows: Gravimetric = 0.92432 × Bone content +39.0633. The loss rate of lumbar bone mineral content in women of all ages before and after menopause in Shenzhen gradually increased, while the average annual loss rate of cancellous bone and clumsy bone was 1.38% and 0.84% respectively. The bone mineral content (135.31 ± 18.36) mg / cm3 was significantly higher in women from 50 to 59 in Shenzhen (20.21 ± 37.40), (116.7 ± 26.6) and (119.5 ± 27.1) mg / cm3 than in Changchun, t = 2.002,3.383,3.636, P <0.05 ~ 0.01)