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胰腺癌作为一种恶性程度很高的消化道肿瘤,近年来发病率有明显升高的趋势,外科手术是目前唯一可能治愈的治疗手段。但胰腺癌起病多隐匿,发现时常已伴有淋巴结转移或邻近血管侵犯,因此手术切除率低,复发率高。国内外外科医师一直致力于改进术式以提高术后的远期疗效,在标准胰十二指肠切除术的基础上出现了以提高根治切除率为目的的扩大切除术。该文就扩大胰十二指肠切除术的病理生理基础、手术范围、适应证及手术难点等予以综述。
Pancreatic cancer as a highly malignant gastrointestinal tumor, the incidence in recent years, there was a clear trend of rising, surgery is the only possible cure for the treatment. However, the incidence of pancreatic cancer more occult, found that often accompanied by lymph node metastasis or adjacent vascular invasion, so the surgical resection rate is low, the recurrence rate. Surgeons at home and abroad have been devoting themselves to improving the surgical procedures to improve the long-term postoperative curative effect. Based on the standard pancreatoduodenectomy, there is an enlarged resection aimed at improving the radical resection rate. This article expands the pathophysiology of pancreatoduodenectomy, the scope of surgery, indications and surgical difficulties are reviewed.