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本文首次证明经照射减毒的尾蚴接种的鼠体内,具有免疫效应机制。实验用6～8周龄雌鼠C57BL/6J和C3H/HeN。曼氏血吸虫尾蚴NMRI株,按Gazzinelli等(1933)的方法制备血吸虫童虫,James等(1981)方法制备可溶性血吸虫成虫抗原(SWAP)。免疫小鼠系按Minard等(1978)的方法,用经~(60COr-射线50Krad
This article for the first time demonstrated that mice immunized with attenuated cercariae had an immune response mechanism. Six to eight-week-old female C57BL / 6J and C3H / HeN mice were used in the experiment. Schistosoma mansoni NMRI strain, according to Gazzinelli et al (1933) method for the preparation of schistosomula Schistosoma japonicum, James et al (1981) Preparation of soluble schistosoma japonicum antigen (SWAP). Mice were immunized according to the method of Minard et al. (1978) using ~ (60COr-ray 50 Krad