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目的探讨放射治疗(放疗)联合靶向药物应用于食管癌患者治疗的临床效果。方法 174例食管癌患者,随机分为对照组和观察组,各87例。对照组给予单纯放疗,观察组给予放疗联合靶向药物。观察患者治疗后的毒副作用以及临床疗效。结果观察组患者治疗后的临床有效率为78.16%,优于对照组的48.28%(P<0.05);观察组患者治疗后各不良反应均少于对照组,且食管炎和皮疹发生率明显低于对照组(P<0.05)。结论对食管癌患者应用放疗联合靶向药物进行治疗时具有较好的临床效果,值得临床推广。
Objective To investigate the clinical effects of radiotherapy (radiotherapy) combined with targeted drugs in the treatment of esophageal cancer patients. Methods 174 cases of esophageal cancer patients were randomly divided into control group and observation group, 87 cases each. The control group was given radiotherapy alone, and the observation group was given radiotherapy combined with targeted drugs. Observed patients after treatment side effects and clinical efficacy. Results The clinical effective rate of the observation group was 78.16% after treatment, which was better than that of the control group (48.28%, P <0.05). The adverse reactions of the observation group were less than those of the control group after treatment, and the incidence of esophagitis and rash was significantly lower In the control group (P <0.05). Conclusion The application of radiotherapy combined with targeted drugs in patients with esophageal cancer treatment has a good clinical effect, is worth clinical promotion.