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荨麻疹性血管炎是以临床上的荨麻疹,组织学的血管炎,红细胞沉降率升高,有免疫复合物参与疾病过程的证据为特征的。多种标准已用于荨麻疹性血管炎的诊断和慢性荨麻疹的分类。本研究是用保存和检查真皮微血管系统的最适当的固定方法制得Epon包埋的半薄切片,这样能按照有无明显的内皮细胞病理学改变来分类。然后,把合并存在的免疫学异常与按血管周围浸润划分的三级分类所得结果比较,并加以讨论。皮损的活组织标本来自15例表现为荨麻疹损害的病人。分别用半浓度的Karnovsky溶液固定和
Urticaria vasculitis is characterized by clinical evidence of urticaria, histological vasculitis, elevated erythrocyte sedimentation rates, and the involvement of immune complexes in the disease process. Various criteria have been used for the diagnosis of urticaria and classification of chronic urticaria. In this study, Epon-embedded semi-thin sections were prepared using the most appropriate fixation method for preservation and examination of the dermal microvasculature, which can be categorized by the presence or absence of significant changes in endothelial cell pathology. The combined immunological abnormalities were then compared with the results of the three-level classification of perivascular infiltrates and discussed. The biopsy specimens were collected from 15 patients with urticaria lesions. Respectively with a half concentration of Karnovsky solution and fixed