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作者把25例拟行停用控制通气的急性呼吸衰竭患者随机分为2组,12例用呼气末5厘米水柱正压呼吸(正压组),13例为非正压呼吸(非正压组)。结果;非正压组者的肺泡-动脉氧张力梯度平均增加102±35毫米汞柱,而正压组仅增加10±22毫米汞柱(P<0.03)。正压组患者的肺活量及最大吸气力亦有明显改善,其肺活量增加258±108毫升(P<0.05),吸气力增加—15±5厘米水柱(P<0.01)。非正压组这些测定无明显改变。
The authors randomized 25 patients with acute respiratory failure who were scheduled to discontinue controlled ventilation into two groups, 12 patients with positive end-expiratory breathing (positive pressure group) with 5 cm of water column, and 13 patients with non-positive pressure breathing (non-positive pressure group). Results: Alveolar-arterial oxygen tension gradient increased by 102 ± 35 mmHg on average in non-positive pressure group and only increased by 10 ± 22 mmHg (P <0.03) in positive pressure group. The vital capacity and maximum inspiratory capacity of patients in positive pressure group also improved significantly. The vital capacity increased 258 ± 108 ml (P <0.05) and the inspiratory force increased -15 ± 5 cm (P <0.01). These measurements did not change significantly in the non-positive pressure group.