Inhibitory Effects of Cypermethrin on Interactions of the Androgen Receptor with Coactivators ARA70

• 作 者: DING Zhen SHEN Jun Yu HONG Jia
• 机 构: SchoolofPublicHealth
• 出 处: 生物医学与环境科学:英文版
• 发表日期: 2020年3期
• 关键词: CYPERMETHRIN ANDROGEN receptor signaling ANDROGEN receptor-associated PROTEIN 70
• 基金项目: supported by National Natural Science Foundations of China[No.81872647],the Natural Science Foundation of the Jiangsu Higher Education Institutions of China[19KJB330007].

Objective The purpose of this study was to investigate the anti-androgenic mechanism of cypermethrin involving coactivators.Methods Mammalian two-hybrid assays were performed to study the effects of cypermethrin on interactions of the androgen receptor(AR