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肉毒梭菌 (C型 )灭活疫苗又称肉毒梭菌中毒症 (C型 )灭活疫苗。本品系用免疫原性良好的C型肉毒梭菌 ,接种于适宜的培养基 ,将培养物经甲醛溶液灭活脱毒后 ,加氢氧化铝胶制成。主要用于预防牛、羊、骆驼、水貂的C型肉毒梭菌中毒症。肉毒梭菌 (C型 )灭活疫苗的效力检验方法 ,长期以来一直采用传统的本动物攻毒法 ,不仅检验程序复杂 ,而且要使用大量的本动物 (羊 ) ,检验周期长、技术落后。而中国兽医药品监察所于近年内在研究梭菌干粉苗的过程中 ,研究出一种用“血清中和试验的方法代替本动物攻毒法”的效检技术 ,此项检验技术科学简便、容易操作、实用性强 ,而且检验成本可下降 75 %。对今后的检验工作具有一定的推动性和实用性。
Clostridium botulinum (C type) inactivated vaccine, also known as Clostridium botulinum toxin (C type) inactivated vaccine. This strain of good immunogenicity of C-type Clostridium botulinum, inoculated in appropriate medium, the culture inactivated by formaldehyde solution after detoxification, made of aluminum hydroxide gel. Mainly used to prevent cattle, sheep, camels, mink C. botulinum poisoning. Clostridium botulinum (C type) inactivated vaccine efficacy test methods, has long been the traditional method of animal poisoning, not only the test procedure is complicated, but also to use a large number of the animals (sheep), the test cycle is long, backward technology . In recent years, the China Veterinary Drug Administration has been studying the efficacy of clostridial dry powder vaccine in the course of researching and developing an effective screening test that uses the serum neutralization test in place of the animal inoculation. This test is scientifically simple and easy Operation, practicality, and testing costs can be reduced by 75%. The test for the future has a certain degree of promotion and practicality.