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格林——巴利综合症是因感染或血清注射、免疫接种诱发的自身免疫性疾病.病理改变除侵犯脊神经根和脊神经外,常侵犯颅神经,有时可侵犯脊膜、脊髓和脑。多数病人在发病前有上呼吸道感染和胃肠道感染等症状。通常为亚急性起病,多数3—5天达高峰。主要症状是肢体对称性瘫痪,感觉异常和脑脊液中蛋白细胞分离现象。瘫痪常自下肢开始,很快扩展到上肢及躯干,仅有少数病人从上肢开始,一般呈对称性分布,严重者呼吸肌麻痹,呼吸困难,发音及吞咽困难,大小便、沁汗等障碍,多数病人亦有肢体或全身性肌肉的自发性疼痛。
Guillain-Barre syndrome is an autoimmune disease induced by infection or serum injection and immunization.Pathological changes often invade cranial nerves and may invade the dura, spinal cord and brain in addition to the invasion of the spinal nerve roots and spinal nerves. Most patients before the onset of upper respiratory tract infections and gastrointestinal infections and other symptoms. Usually subacute onset, the majority of the peak 3-5 days. The main symptoms are paralysis of limb symmetry, abnormal sensations and the separation of protein cells in cerebrospinal fluid. Paralysis often begins from the lower limbs, and soon expands to the upper extremities and torso, only a few patients from the upper limb began, the general symmetrical distribution, respiratory muscle paralysis in severe cases, dyspnea, dysarthria, difficulty swallowing, urination, Most patients also have spontaneous pain in limbs or body muscles.