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通过胃镜对２００例乙型肝炎病毒（ＨＢＶ）慢性感染者进行了胃粘膜组织病理检查，同时行肝组织病理检查，其中对８０例采用ＡＢＣ法检测胃粘膜中的ＨＢｓＡｇ和ＨＢｃＡｇ。结果ＨＢｓＡｇ阳性２９例。ＨＢｃＡｇ阳性１２例；受感染的胃粘膜细胞呈簇样分布于胃粘膜组织中，以胃窦部腺泡细胞为主。所有患者的胃粘膜均有不同程度的病变，以胃窦部为甚，且病变程度和患病率显著高于对照组。胃粘膜中ＨＢＶ抗原阳性者病变程度较重，可能与ＨＢＶ感染有关。
Gastric mucosa histopathological examination was performed on 200 cases of chronic hepatitis B virus infection by gastroscopy, and liver histopathology was also performed. Eighty cases were examined by ABC method to detect HBsAg and HBcAg in gastric mucosa. Results HBsAg positive in 29 cases. HBcAg positive in 12 cases; infected gastric mucosal cells were clustered in the gastric mucosa tissue to the main gastric acinar cells. All patients had different degrees of gastric mucosal lesions, gastric antrum is even worse, and the degree of disease and prevalence was significantly higher than the control group. Gastric mucosa HBV antigen-positive patients with severe lesions may be related to HBV infection.