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目的:探索清热化痰饮配合西药治疗小儿代谢综合征(MS)的临床疗效及对患儿体质量指数(BMI)的影响。方法:选择2014年1月—2015年12月期间于医院检查确诊并接受治疗的90例代谢综合征患儿纳入临床研究,根据其入院时间进行编号,其中被编为单号者45例为对照组,采取常规西药治疗,编为双号者45例为观察组,在西药治疗基础上配合清瘀化痰饮,分析临床治疗效果并进行差异分析。结果:观察组患者治疗后腰围(85.23±1.67)cm、BMI(24.10±1.54)均较其治疗前和对照组明显减少,各项差异有统计学意义(P<0.05)。观察组患者治疗后FBG(7.30±0.76)mmol/L、PBG(8.43±0.76)mmol/L、SBP(120.25±5.56)mm Hg、DBP(75.85±4.01)mm Hg,均较其治疗前和对照组有明显减少,各项差异均有统计学意义(P<0.05)。观察组患者治疗后TC(4.48±0.55)mmol/L、TG(1.78±0.27)mmol/L、LDL(2.80±0.33)mmol/L,均较其治疗前和对照组有明显减少,各项差异均有统计学意义(P<0.05)。结论:清热化痰饮配合西药治疗小儿代谢综合征能调节其糖脂代谢紊乱,且在控制血压,减轻体质量方面效果显著,可作为临床治疗的首选方案。
Objective: To explore the clinical curative effect of Qingre Huatan Decoction combined with Western medicine on children with metabolic syndrome (MS) and its effect on body mass index (BMI) in children. Methods: Ninety patients with metabolic syndrome diagnosed and treated in our hospital from January 2014 to December 2015 were enrolled in the clinical study, and were enrolled according to the time of their admission. Among them, 45 patients who were singled were the control group Group, taking conventional Western medicine, compiled as a double number 45 cases for the observation group, on the basis of Western medicine with clear stasis phlegm, analysis of clinical treatment and analysis of differences. Results: After treatment, waist circumference (85.23 ± 1.67 cm) and BMI (24.10 ± 1.54) in the observation group were significantly decreased compared with those before treatment and in the control group (all P <0.05). The FBG (7.30 ± 0.76) mmol / L, PBG (8.43 ± 0.76) mmol / L, SBP (120.25 ± 5.56) mm Hg and DBP (75.85 ± 4.01) mm Hg in the observation group were significantly higher than those before treatment and before treatment There was a significant reduction in the group, the differences were statistically significant (P <0.05). Compared with the control group and before treatment, TC (4.48 ± 0.55) mmol / L, TG (1.78 ± 0.27) mmol / L and LDL (2.80 ± 0.33) mmol / L decreased after treatment in observation group All were statistically significant (P <0.05). Conclusion: Qingre Huatan Decoction combined with western medicine treatment of children with metabolic syndrome can regulate its glucose and lipid metabolism disorders, and in the control of blood pressure, reduce body mass, the effect is significant, as the preferred solution for clinical treatment.