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本文作者应用随机对照研究方法,比较了噻肟单酰胺菌素(aztreonam)和氯霉素治疗儿童伤寒的安全性和疗效。选择经临床和细菌学证实的36例伤寒患儿为研究对象,年龄2～16岁。入院时均有发热,并至少出现以下2种症状和体征:腹泻或便秘;脱水;腹痛或触痛;节段性肠梗阻;肝肿大和/或脾肿大;玫瑰疹;咳嗽;
The authors apply a randomized controlled study to compare the safety and efficacy of aztreonam and chloramphenicol in the treatment of typhoid fever in children. Thirty-six children with typhoid fever clinically and bacteriologically confirmed were selected as study subjects, aged 2-16 years. Fever on admission with at least two symptoms and signs: diarrhea or constipation; dehydration; abdominal pain or tenderness; segmental ileus; hepatomegaly and / or splenomegaly; roseola; cough;